Issue · Apr 2026New this week: evidence-first longevity readsThe newsletter — one essay, Sunday morningsArchive access — every article, free to readPodcast coming soon — NotebookLM sessionsLetters from readers — reply to any emailIssue · Apr 2026New this week: evidence-first longevity readsThe newsletter — one essay, Sunday morningsArchive access — every article, free to readPodcast coming soon — NotebookLM sessionsLetters from readers — reply to any email

Brain.

Evidence-led reading on brain from the HL Benefits desk. Long reads, careful guides, and the boring-but-true positions the research keeps settling on.

In this section
18longreads
Newest
Apr 142026
Section since
2016archive
Reading time
~8min average
This week's longread

Ketogenic Diet for Mental Health: Depression, Bipolar, and Brain Energy Theory

Clinical trials at Stanford, Harvard, and Edinburgh are testing whether ketogenic diets can treat depression and bipolar disorder by providing the brain with an alternative fuel source.

Read the articleHL Benefits Editorial · Apr 14, 2026
Ketogenic Diet for Mental Health: Depression, Bipolar, and Brain Energy TheoryPhotograph · HL Benefits
§ 01

The latest, in long form.

Browse all 18
Focused Ultrasound for Mental Health: The Non-Invasive Brain Treatment You Haven't Heard Of
CoverBrain

Focused Ultrasound for Mental Health: The Non-Invasive Brain Treatment You Haven't Heard Of

Sound waves can now reach brain structures linked to depression and anxiety without surgery. Clinical trials show significant symptom reduction in just three weeks.

Apr 11
Ketamine Therapy for Depression: How It Works, Cost, and Where to Find It
Brain

Ketamine Therapy for Depression: How It Works, Cost, and Where to Find It

Ketamine therapy offers rapid relief for treatment-resistant depression, with effects in 40 minutes. Learn about costs, types, finding providers, and risks.

Apr 1
Psilocybin Microdosing: Benefits, Risks, and What 10 Million Americans Are Doing
Brain

Psilocybin Microdosing: Benefits, Risks, and What 10 Million Americans Are Doing

10 million Americans microdosed last year. Brain scans show real changes, but mood and cognition remain indistinguishable from placebo.

Apr 1
Neurowellness: The #1 Wellness Trend of 2026 and How to Regulate Your Nervous System
Brain

Neurowellness: The #1 Wellness Trend of 2026 and How to Regulate Your Nervous System

The Global Wellness Summit named neurowellness the top trend for 2026. Here is the science behind vagal tone, HRV, and a daily protocol for nervous system regulation.

Mar 31
From the editorApr letterHL Benefits MagazineHL Benefits Editorial Team

We started this section because the conversation about brain had become unbearable — too loud, too certain, too often selling something. The boring middle — what the evidence actually supports, repeated across decades, written without a brand to defend — is not a position you can monetize, but it is the position the research keeps quietly settling on.

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Companion sections.

All sections →
160 articles · ongoing

Health

A companion section to brain, with its own evidence-led reading list.

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71 articles · ongoing

Food & Nutrition

A companion section to brain, with its own evidence-led reading list.

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29 articles · ongoing

Weight Loss

A companion section to brain, with its own evidence-led reading list.

Read the section
§ 03

Definitive guides.

All guides →
Men's Mental Health: Why Therapy for Men Is Surging and How to Start
Guide

Men's Mental Health: Why Therapy for Men Is Surging and How to Start

Men's therapy use surged 36% between 2019 and 2021. Here's what changed, what works, and how to get started.

Mar 30
Phosphatidylserine for Memory, Cortisol, and Brain Health
Guide

Phosphatidylserine for Memory, Cortisol, and Brain Health

Phosphatidylserine supports memory, lowers cortisol, and protects aging neurons. Here is what the clinical evidence actually shows.

Mar 22
A note on evidence

A claim about brain is not a study. A study is not a meta-analysis. A meta-analysis is not a guideline. The article doesn't fit on a label.

HL Benefits Editorial Team · on the standards we hold ourselves to
§ 04

On our desk this week.

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