Issue · May 2026New this week: evidence-first longevity readsThe newsletter — one essay, Sunday morningsArchive access — every article, free to readPodcast coming soon — NotebookLM sessionsLetters from readers — reply to any emailIssue · May 2026New this week: evidence-first longevity readsThe newsletter — one essay, Sunday morningsArchive access — every article, free to readPodcast coming soon — NotebookLM sessionsLetters from readers — reply to any email

Brain.

Evidence-led reading on brain from the HL Benefits desk. Long reads, careful guides, and the boring-but-true positions the research keeps settling on.

In this section
21longreads
Newest
May 162026
Section since
2016archive
Reading time
~8min average
This week's longread

Dihexa: The Synapse-Building Peptide Reportedly 7× Stronger Than BDNF

Dihexa is the peptide marketed as 7x stronger than BDNF. The honest version: zero human trials, a retracted paper, and a failed Phase 2/3 trial.

Read the articleHL Benefits Editorial · May 16, 2026
Dihexa: The Synapse-Building Peptide Reportedly 7× Stronger Than BDNFPhotograph · HL Benefits
§ 01

The latest, in long form.

Browse all 21
Cerebrolysin: The Memory Peptide Used in 50 Countries — But Not the U.S.
CoverBrain

Cerebrolysin: The Memory Peptide Used in 50 Countries — But Not the U.S.

Cerebrolysin is the porcine-brain peptide mixture European neurologists use for stroke recovery and vascular dementia. The FDA has never approved it. The Cochrane evidence is mixed, the gray market…

May 15
Electric Medicine and Brain Stimulation: TMS, tDCS, and the Future of Mental Health
Brain

Electric Medicine and Brain Stimulation: TMS, tDCS, and the Future of Mental Health

A guide to non-invasive brain stimulation covering TMS, tDCS, the Stanford 5-day protocol, UCLA research, and FDA-cleared devices for mental health.

Apr 9
Dopamine Detox: What the Neuroscience Actually Says About Resetting Your Brain
Brain

Dopamine Detox: What the Neuroscience Actually Says About Resetting Your Brain

Your brain can't be 'detoxed' from dopamine. Here's what the neuroscience actually says about reward prediction, receptor recovery, and what works instead.

Apr 8
Bright Light Therapy for Depression and SAD: Devices, Timing, and Protocol
Brain

Bright Light Therapy for Depression and SAD: Devices, Timing, and Protocol

A 10,000 lux light box can match antidepressants for both seasonal and non-seasonal depression. Here's the evidence-based protocol, device comparison, and who should avoid it.

Apr 5
From the editorMay letterHL Benefits MagazineHL Benefits Editorial Team

We started this section because the conversation about brain had become unbearable — too loud, too certain, too often selling something. The boring middle — what the evidence actually supports, repeated across decades, written without a brand to defend — is not a position you can monetize, but it is the position the research keeps quietly settling on.

§ 02

Companion sections.

All sections →
177 articles · ongoing

Health

A companion section to brain, with its own evidence-led reading list.

Read the section
72 articles · ongoing

Food & Nutrition

A companion section to brain, with its own evidence-led reading list.

Read the section
34 articles · ongoing

Weight Loss

A companion section to brain, with its own evidence-led reading list.

Read the section
§ 03

Definitive guides.

All guides →
Ketamine Therapy for Depression: How It Works, Cost, and Where to Find It
Guide

Ketamine Therapy for Depression: How It Works, Cost, and Where to Find It

Ketamine therapy offers rapid relief for treatment-resistant depression, with effects in 40 minutes. Learn about costs, types, finding providers, and risks.

Apr 1
Psilocybin Microdosing: Benefits, Risks, and What 10 Million Americans Are Doing
Guide

Psilocybin Microdosing: Benefits, Risks, and What 10 Million Americans Are Doing

10 million Americans microdosed last year. Brain scans show real changes, but mood and cognition remain indistinguishable from placebo.

Apr 1
A note on evidence

A claim about brain is not a study. A study is not a meta-analysis. A meta-analysis is not a guideline. The article doesn't fit on a label.

HL Benefits Editorial Team · on the standards we hold ourselves to
§ 04

On our desk this week.

More from the desk →
§ 05

Quick reads.

All 21
01

Foods for Thought: Natural Brain Supplements That Science Supports

Nov 8
02

The Brain: Anatomy, Function, and Common Medical Conditions

Oct 18
03

Depression and Complementary Health Approaches: The Ultimate Evidence Guide

Jul 16
04

Nootropics for the Mental Edge: The Evidence-Based Ultimate Guide

Jun 23

The BriefOne slow read about brain, every Thursday morning.

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