Issue · Jun 2026New this week: evidence-first longevity readsThe newsletter — one essay, Sunday morningsArchive access — every article, free to readPodcast coming soon — NotebookLM sessionsLetters from readers — reply to any emailIssue · Jun 2026New this week: evidence-first longevity readsThe newsletter — one essay, Sunday morningsArchive access — every article, free to readPodcast coming soon — NotebookLM sessionsLetters from readers — reply to any email

Brain.

Evidence-led reading on brain from the HL Benefits desk. Long reads, careful guides, and the boring-but-true positions the research keeps settling on.

In this section
26longreads
Newest
May 302026
Section since
2016archive
Reading time
~8min average
This week's longread

Selank vs. Semax: The Russian Brain Peptides Silicon Valley Is Obsessed With

Two heptapeptides from one Moscow lab became biohacker staples for anxiety and focus. Here is what the Russian science shows and where US regulation stands.

Read the articleHL Benefits Editorial · May 30, 2026
Selank vs. Semax: The Russian Brain Peptides Silicon Valley Is Obsessed WithPhotograph · HL Benefits
§ 01

The latest, in long form.

Browse all 26
PT-141 for Men: The Brain-Based Erection Peptide That Works When Viagra Doesn't
CoverBrain

PT-141 for Men: The Brain-Based Erection Peptide That Works When Viagra Doesn't

PT-141 (bremelanotide) activates melanocortin receptors in the hypothalamus to initiate erection from the brain down, rescuing 33.5% of men who fail Viagra. Approved as Vyleesi for women only —…

May 30
Dihexa: The Synapse-Building Peptide Reportedly 7× Stronger Than BDNF
Brain

Dihexa: The Synapse-Building Peptide Reportedly 7× Stronger Than BDNF

Dihexa is the peptide marketed as 7x stronger than BDNF. The honest version: zero human trials, a retracted paper, and a failed Phase 2/3 trial.

May 16
Cerebrolysin: The Memory Peptide Used in 50 Countries — But Not the U.S.
Brain

Cerebrolysin: The Memory Peptide Used in 50 Countries — But Not the U.S.

Cerebrolysin is the porcine-brain peptide mixture European neurologists use for stroke recovery and vascular dementia. The FDA has never approved it. The Cochrane evidence is mixed, the gray market…

May 15
Anxiety Peptides: How Selank Compares to Xanax (Without the Withdrawal)
Brain

Anxiety Peptides: How Selank Compares to Xanax (Without the Withdrawal)

A detailed comparison of Selank peptide and Xanax for anxiety, covering mechanisms, clinical trial data, withdrawal risk, and regulatory realities.

May 13
From the editorMay letterHL Benefits MagazineHL Benefits Editorial Team

We started this section because the conversation about brain had become unbearable — too loud, too certain, too often selling something. The boring middle — what the evidence actually supports, repeated across decades, written without a brand to defend — is not a position you can monetize, but it is the position the research keeps quietly settling on.

§ 02

Companion sections.

All sections →
198 articles · ongoing

Health

A companion section to brain, with its own evidence-led reading list.

Read the section
77 articles · ongoing

Food & Nutrition

A companion section to brain, with its own evidence-led reading list.

Read the section
38 articles · ongoing

Weight Loss

A companion section to brain, with its own evidence-led reading list.

Read the section
§ 03

Definitive guides.

All guides →
Ketogenic Diet for Mental Health: Depression, Bipolar, and Brain Energy Theory
Guide

Ketogenic Diet for Mental Health: Depression, Bipolar, and Brain Energy Theory

Clinical trials at Stanford, Harvard, and Edinburgh are testing whether ketogenic diets can treat depression and bipolar disorder by providing the brain with an alternative fuel source.

Apr 14
Focused Ultrasound for Mental Health: The Non-Invasive Brain Treatment You Haven't Heard Of
Guide

Focused Ultrasound for Mental Health: The Non-Invasive Brain Treatment You Haven't Heard Of

Sound waves can now reach brain structures linked to depression and anxiety without surgery. Clinical trials show significant symptom reduction in just three weeks.

Apr 11
A note on evidence

A claim about brain is not a study. A study is not a meta-analysis. A meta-analysis is not a guideline. The article doesn't fit on a label.

HL Benefits Editorial Team · on the standards we hold ourselves to
§ 04

On our desk this week.

More from the desk →
§ 05

Quick reads.

All 26
01

Phosphatidylserine for Memory, Cortisol, and Brain Health

Phosphatidylserine supports memory, lowers cortisol, and protects aging neurons. Here is…

Mar 22
02

Mediterranean Diet for Brain Health and Longevity: What the Research Shows

Current research links the Mediterranean diet to up to 30% lower Alzheimer's risk. Learn…

Mar 21
03

Lion's Mane Mushroom for Brain Health and Nerve Regeneration

Evidence-based guide to lion's mane mushroom for brain health, cognitive function, and…

Mar 7
04

Awe Walks: Daily Nature Exposure for Mental Well-Being

A practical, evidence-based guide to awe walks that uses daily nature exposure to reduce…

Nov 11
05

Best Ways to Seriously Improve Your Memory

Jan 22
06

Foods for Thought: Natural Brain Supplements That Science Supports

Nov 8
07

The Brain: Anatomy, Function, and Common Medical Conditions

Oct 18
08

Depression and Complementary Health Approaches: The Ultimate Evidence Guide

Jul 16
§ 06

From the archive.

All 26
Focused professional organizing a cognitive performance plan at a desk with water, coffee, and brain-supportive foods.
Brain

Nootropics for the Mental Edge: The Evidence-Based Ultimate Guide

Jun 23

The BriefOne slow read about brain, every Thursday morning.

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