Issue · Apr 2026New this week: evidence-first longevity readsThe newsletter — one essay, Sunday morningsArchive access — every article, free to readPodcast coming soon — NotebookLM sessionsLetters from readers — reply to any emailIssue · Apr 2026New this week: evidence-first longevity readsThe newsletter — one essay, Sunday morningsArchive access — every article, free to readPodcast coming soon — NotebookLM sessionsLetters from readers — reply to any email
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Compounded Semaglutide: How to Tell a Safe Source from a Dangerous Knockoff
Weight Loss

Compounded Semaglutide: How to Tell a Safe Source from a Dangerous Knockoff

After the FDA declared the semaglutide shortage resolved in February 2025, the legal market for compounded GLP-1s narrowed sharply while a black market expanded. This guide walks through 503A vs 503B vs research peptides, the salt-form red flag, counterfeit incidents on record, and the credentialing checklist and questions that separate a legitimate compounding pharmacy from a dangerous knockoff.

Apr 24 · 16 min readBy J. (JessieLew)
The long read

A slower piece, on one thing.

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Vitamin E for Skin: Benefits, Gummies, and the TikTok Trend Explained
Beauty · In-depth essay

Vitamin E for Skin: Benefits, Gummies, and the TikTok Trend Explained

An evidence-based guide to vitamin E for skin, covering how it works, which forms matter, and what dermatologists say about gummies and the TikTok capsule trend.

Begin reading14 min readBy Jessica Lewis (JessieLew)
Letter from the editorial team

On the quiet parts of getting well.

SURMOUNT-5 settled the indirect-comparison era.

Here is what the head-to-head trial actually showed about tirzepatide versus semaglutide for fat loss.

The goal isn’t to be comfortable with change — it’s to be comfortable with one small change, on a schedule, held for a year.

From “Tirzepatide vs. Semaglutide: Which GLP-1 Peptide Actually Melts More Fat?” · The HL Benefits Editorial Team · Apr 2026
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The Quiet Podcast · Coming soon

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