Issue · May 2026New this week: evidence-first longevity readsThe newsletter — one essay, Sunday morningsArchive access — every article, free to readPodcast coming soon — NotebookLM sessionsLetters from readers — reply to any emailIssue · May 2026New this week: evidence-first longevity readsThe newsletter — one essay, Sunday morningsArchive access — every article, free to readPodcast coming soon — NotebookLM sessionsLetters from readers — reply to any email

Makeup &
Skincare.

Evidence-led reading on makeup & skincare from the HL Benefits desk. Long reads, careful guides, and the boring-but-true positions the research keeps settling on.

In this section
12longreads
Newest
May 202026
Section since
2026archive
Reading time
~8min average
This week's longread

The Truth About Melanotan II: Tanning, Side Effects, and the "Barbie Drug" Warning

Melanotan II promises a fast tan from a nasal spray or syringe, but the UK MHRA declared it illegal in 2008, the Cleveland Clinic calls it possibly unsafe, and JAMA Dermatology has documented dysplastic mole changes in users. Here is the full evidence-based picture of the 'Barbie drug' — its mechanism, its side…

Read the articleHL Benefits Editorial · May 20, 2026
The Truth About Melanotan II: Tanning, Side Effects, and the "Barbie Drug" WarningPhotograph · HL Benefits
§ 01

The latest, in long form.

Browse all 12
Marine Collagen vs. Bovine Collagen: A Buyer's Comparison for Skin and Joints
CoverMakeup & Skincare

Marine Collagen vs. Bovine Collagen: A Buyer's Comparison for Skin and Joints

Marine and bovine collagen differ in collagen types, absorption, and clinical evidence. This guide compares both for skin and joint goals.

May 19
Why Peptide Eye Creams Outperform $200 Serums for Crow's Feet
Makeup & Skincare

Why Peptide Eye Creams Outperform $200 Serums for Crow's Feet

Peptide eye creams can beat luxury serums when the formula supports hydration, barrier comfort, and realistic wrinkle care.

May 2
Matrixyl 3000: The Anti-Aging Peptide That Quietly Made It Into Every Drugstore
Makeup & Skincare

Matrixyl 3000: The Anti-Aging Peptide That Quietly Made It Into Every Drugstore

Matrixyl 3000 has real peptide science behind it, but the best claims still need context before you buy another serum.

May 2
Can You Layer Peptides with Retinol? The Mistake Most People Make
Makeup & Skincare

Can You Layer Peptides with Retinol? The Mistake Most People Make

Peptides and retinol can share a routine, but copper peptides and aggressive layering need more care.

Apr 29
From the editorMay letterHL Benefits MagazineHL Benefits Editorial Team

We started this section because the conversation about makeup & skincare had become unbearable — too loud, too certain, too often selling something. The boring middle — what the evidence actually supports, repeated across decades, written without a brand to defend — is not a position you can monetize, but it is the position the research keeps quietly settling on.

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Companion sections.

All sections →
178 articles · ongoing

Health

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Food & Nutrition

A companion section to makeup & skincare, with its own evidence-led reading list.

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34 articles · ongoing

Weight Loss

A companion section to makeup & skincare, with its own evidence-led reading list.

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§ 03

Definitive guides.

All guides →
GHK-Cu Skincare: The 30-Year-Old Discovery Now Outselling Vitamin C Serums
Guide

GHK-Cu Skincare: The 30-Year-Old Discovery Now Outselling Vitamin C Serums

GHK-Cu is trending as a vitamin C alternative, but the evidence is more nuanced than the hype.

Apr 29
Copper Peptides vs. Retinol: Which One Wins the Anti-Wrinkle Battle?
Guide

Copper Peptides vs. Retinol: Which One Wins the Anti-Wrinkle Battle?

Retinol has stronger wrinkle evidence; copper peptides offer repair support for irritation-prone skin.

Apr 28
A note on evidence

A claim about makeup & skincare is not a study. A study is not a meta-analysis. A meta-analysis is not a guideline. The article doesn't fit on a label.

HL Benefits Editorial Team · on the standards we hold ourselves to
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On our desk this week.

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